01 - Preheat the oven to 350°F. Grease a 2-quart baking dish.
02 - Boil elbow macaroni in salted water until just al dente. Drain and set aside.
03 - Melt butter in a large saucepan over medium heat. Whisk in flour and cook until lightly golden, about 1–2 minutes.
04 - Gradually whisk in whole milk to the roux, stirring continuously to prevent lumps. Cook until thickened, approximately 5 minutes. Stir in Dijon mustard, garlic powder, onion powder, salt, and pepper.
05 - Remove the sauce from heat. Incorporate grated cheddar and Gruyère cheeses until fully melted and smooth.
06 - Mix the cooked macaroni into the cheese sauce thoroughly, then transfer to the prepared baking dish.
07 - In a separate bowl, combine fresh breadcrumbs, melted butter, and grated Parmesan cheese. Evenly sprinkle this mixture over the macaroni and cheese.
08 - Bake in the preheated oven for 30 to 35 minutes, until the top is golden brown and the dish is bubbling.
09 - Allow the dish to rest for 5 minutes before serving to set.